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Test ABMM Pass4sure & Exam ABMM Sample
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American Society of Microbiology ABMM Sample Questions (Q185-Q190):
NEW QUESTION # 185
A 6-year-old child presents with a pharyngitis characterized by a grayish-white pseudomembrane covering the tonsils and posterior pharynx. Gram stain of the membrane reveals Gram-positive bacilli. Culture on Loeffler's medium shows growth of metachromatic granules. The MOST significant virulence factor associated with this organism's pathogenicity is:
- A. Streptolysin O
- B. Diphtheria toxin
- C. Hyaluronidase
- D. Protein A
Answer: B
NEW QUESTION # 186
A clinical microbiology laboratory is validating a new point-of-care test for the rapid detection of influenza A and B viruses. To accurately determine the clinical sensitivity of the test, it should be compared to a gold standard method using:
- A. A panel of known positive and negative samples stored at room temperature.
- B. Spiked samples containing known concentrations of influenza antigens.
- C. Samples from patients with other respiratory viral infections to assess cross-reactivity.
- D. A large number of prospectively collected clinical samples from patients with suspected influenza, with results confirmed by RT-PCR.
Answer: D
NEW QUESTION # 187
A patient with a history of travel to Southeast Asia presents with fever, severe headache, and altered mental status. CSF analysis reveals lymphocytic pleocytosis and elevated protein, but routine bacterial and viral cultures are negative. Serological testing of CSF is positive for IgM antibodies against Japanese encephalitis virus. The MOST likely mode of transmission for this infection is:
- A. Ingestion of contaminated food or water.
- B. Respiratory droplets from an infected individual.
- C. Direct contact with infected animals.
- D. Bite of an infected mosquito.
Answer: D
NEW QUESTION # 188
The azole class of antifungal agents (e.g., fluconazole, voriconazole) exerts its effect primarily by inhibiting which fungal-specific enzyme involved in membrane synthesis?
- A. Beta-(1,3)-glucan synthase
- B. Lanosterol 14-alpha-demethylase
- C. Chitin synthase
- D. Squalene epoxidase
Answer: B
NEW QUESTION # 189
During a community outbreak of influenza, a public health laboratory performs rapid antigen testing on nasopharyngeal swabs. A test for influenza A is positive, but the influenza B test is negative. Subsequently, RT-PCR is performed on the same sample, and it is negative for both influenza A and B viral RNA. The MOST likely explanation for this discordant result is:
- A. The patient was infected with a novel influenza strain not detected by either assay.
- B. The RT-PCR assay has a high limit of detection, missing a low viral load.
- C. The rapid antigen test yielded a false positive result, and the RT-PCR was a true negative.
- D. The rapid antigen test has low sensitivity, resulting in a false positive.
Answer: C
NEW QUESTION # 190
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